程津培  教授,中科院院士

基础分子科学中心主任

 

研究方向:

物理有机化学
有机能量学
化学键键能的测定与计算

程津培,有机化学家,中国科学院院士(2001),第三世界科学院院士(TWAS,2001),清华大学基础分子科学中心主任(2012)。1975年毕业于天津师范学院,1981年获南开大学硕士,1987年获美国西北大学博士,1988年到南开大学工作(1995-2000年任副校长),2000-2008年担任国家科技部副部长。现任全国人大常委、教科文卫委员会副主任、致公党中央副主席、国家教育咨询委员会委员、国家科技奖励委员会委员、欧美同学会副会长等职。

程津培教授主要从事物理有机化学研究,主要研究课题包括有机溶剂中各类化学键键能的方法学和实验测定、自由基稳定性理论、一氧化氮(NO)转移的热力学驱动力和机理、NADH辅酶模型的反应的热力学,动力学及机理、负氢热力学、叶立德(Ylide)稳定性的统一标度、离子液体中化合物pKa测定和有机小分子催化不对称有机反应机理等。

程津培教授在Science,Angewandte Chemie Internal Edition,Journal of the American Chemistry Society,The Journal of Organic Chemistry,Organic Letters,Chemistry - an European Journal,Chemical Communications等国内外著名刊物上发表了学术论文200余篇。这些论文已被国际论文他引5000余次,其中单篇最高他引达200余次。2005年获得何梁何利科学与技术进步奖。

 

代表性论文

  1. Xue, X.; Ji, P.; Zhou, B.; Cheng, J.-P. The Essential Role of Bond Energetics in C-H Activation/Functionalization. Chem. Rev., 2017, 117, 8622–8648.
  2. Yang, C.; Wang, J.; Liu, Y.; Ni, X.; Li, X.; Cheng, J.-P. Study on the Catalytic Behavior of Bifunctional Hydrogen-Bonding Catalysts Guided by Free Energy Relationship Analysis of Steric Parameters. Chem. Eur. J. 2017, 23, 5488-5497.
  3. Li, Z.; Li, X.; Cheng, J.-P. An Acidity Scale of Triazolium-Based NHC Precursors in DMSO. J. Org. Chem. 2017, 82, 9675-9681.
  4. Mao, C.; Wang, Z.-D.; Wang, Z.; Ji, P.; Cheng, J.-P. Weakly Polar Aprotic Ionic Liquids Acting as Strong Dissociating Solvent: A Typical “Ionic Liquid Effect” Revealed by Accurate Measurement of Absolute pKa of Ylide Precursor Salts. J. Am. Chem. Soc. 2016, 138, 5523.
  5. Dong, N.; Zhang, Z.-P.; Xue, X.-S.; Li, X.; Cheng, J.-P. Phosphoric Acid Catalyzed Asymmetric 1,6-Conjugate Addition of Thioacetic Acid to para-Quinone Methides. Angew. Chem. Int. Ed. 2016, 55, 1460-1464.
  6. Yang, C.; Zhang, E.-G.; Li, X.; Cheng, J.-P. Asymmetric Conjugate Addition of Benzofuran-2-ones to Alkyl 2-Phthalimidoacrylates: Modeling Structure-Stereoselectivity Relationships with Steric and Electronic Parameters. Angew. Chem. Int. Ed. 2016, 55, 6506-6510.
  7. Li, Z.; Li, X.; Ni, X.; Cheng, J.-P. Equilibrium Acidities of Proline Derived Organocatalysts in DMSO. Org. Lett. 2015, 17, 1196-1199.
  8. Wang, Z.-D.; Li, X.; Ji, P.; Cheng, J.-P. Absolute pKas of Sulfonamides in Ionic Liquids: Comparisons to Molecular Solvents. J. Org. Chem. 2016, 81, 11195.
  9. Xue, X.-S.; Wang, Y.; Yang, C.; Ji, P.; Cheng, J.-P. Toward Prediction of the Chemistry in Ionic Liquids: An Accurate Computation of Absolute pK(a) Values of Benzoic Acids and Benzenethiols. J. Org. Chem. 2015, 80, 8997-9006.
  10. Xue, X.; Li, X.; Yu, A.; Yang, C.; Song, C.; Cheng, J.-P. Mechanism and Selectivity of Bioinspired Cinchona Alkaloid Derivatives Catalyzed Asymmetric Olefin Isomerization: A Computational Study J. Am. Chem. Soc. 2013, 135, 7462-7473.

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