Dr. Bi-Jie Li began his undergraduate studies at Peking University and conducted undergraduate research in Prof. Zhang-Jie Shi’s lab. He obtained his bachelor degree in chemistry in 2007. In the same year, he began his graduate studies and worked with Prof. Zhang-Jie Shi at Peking University. In the Prof. Shi group, he developed a variety of methods for selective functionalization of inert C-O and C-H bonds. In the summer of 2012, he moved to University of California, Berkeley where he conducted his postdoctoral work in Prof. John Hartwig's group. While in Berkeley, he worked on catalytic amidation and silylation of aliphatic C-H bonds. In July 2015, he started his independent career in the chemistry department at Tsinghua University as an associate professor.

The Li research group aims to combine organometallic chemistry and physical organic chemistry to tackle challenging problems in organic synthesis. Currently, his research interests focus on transition metal catalyzed enantioselective functionalization of internal alkenes.

Selected Publications

1.Zhao, W.; Lu, H.-X.; Zhang, W.-W.; Li, B.-J. Coordination Assistance: A Powerful Strategy for Metal-Catalyzed Regio- and Enantioselective Hydroalkynylation of Internal Alkenes. Acc. Chem. Res. 2023, 56, 308-321.

2.Zhao, W.; Li, B.-J. Directing Group Repositioning Strategy Enabled Site- and Enantioselective Addition of Heteroaromatic C-H Bond to Acyclic Internal Alkenes. J. Am. Chem. Soc. 2023, DOI: 10.1021/jacs.3c00095.

3. Zhang, W.-W.; Li, B.-J. Enantioselective Hydrosilylation of β,β-Disubstituted Enamides to Construct α-Aminosilanes with Vicinal Stereocenters. Angew. Chem. Int. Ed. 2023, 62, e202214534.

4.Zhao, W.; Chen, K.-Z.; Li, A.-Z.; Li, B.-J. Remote Stereocenter through Amide-Directed, Rhodium-Catalyzed Enantioselective Hydroboration of Unactivated Internal Alkenes. J. Am. Chem. Soc. 2022, 144, 13071-13078.

5.Sun, X.; Lin, E.-Z.; Li, B.-J. Iridium-Catalyzed Branch-Selective and Enantioselective Hydroalkenylation of alpha-Olefins through C-H Cleavage of Enamides. J. Am. Chem. Soc. 2022, 144, 17351-17358.